|
|
|
|
 |
 |
|
|
Title of technology:
|
|
Method of preparing an extract potent in anti-inflammation,
anti-platelet aggregation and anti-fungal activity from Zingiber officinale,
and pharmaceutical compositions containing said extract |
|
Date posted:
|
|
10 February, 2006
|
|
Category:
|
|
Drug discovery, Herbal medicine
|
|
Application:
|
|
Anti-inflammation, anti-platelet aggregation, anti-fungal
|
|
Abstract:
|
|
A method of preparing an extract from Zingiber officinale,
which is potent in anti-inflammation, anti-platelet aggregation and anti-fungal
activity, which includes the following steps: prepare a crude liquid from
rhizomes of ginger by extraction with an organic solvent or supercritical
CO2 or by distillation with steam; introducing the crude liquid to a reverse
phase chromatography column, and eluting the column with water, a first
eluent and a second eluent having a polarity weaker than that of the first
eluent but stronger than that of chlorofrom, so that a first eluate resulting
from elution of the first eluent and a second eluate resulting from elution
of the second eluent are obtained; removing the first eluent and the second
eluent from the first eluate and the second eluate by evaporation, respectively,
so that a first concentrated eluate and a second concentrated eluate are
obtained as the potent extract. The final product or the crude liquid
obtained in the first step may be incorporated into a pharmaceutical composition
together with a suitable carrier of diluent
|
|
Patent information:
|
|
US6274,177B1; US6,946,153B2; NL1018234; CH692272A5; GB2366565
|
|
Development status:
|
|
Preclinical (CMC)
|
|
Type of business
relationship sought:
|
|
Patent licensing
|
Contact: |
|
Ms. CK Liu |
Email: |
|
|
|
Company or institute:
|
|
|
|
|
|
|
Taiwan Life Sciences Weekly
|
 |
|
 |
|
|
 |
 |
|
 |
|
| |
